Maria Arroz, MD Director of the Flow Cytometry Laboratory
CHLO, Hospital S. Francisco Xavier
Lisbon, Portugal

I have been an Infinicyt™ user since 2009 and I find it a very helpful software to screen for and analyse files of hematological malignancies. I like the idea of not using prefixed templates or quadrants and be able to perform a fast sequential analysis to identify and characterize each cellular population. It has some features that I particularly enjoy, namely the Automated Population Separator (APS) which provides a n-dimensional separation of events based on all the parameters in the file. This feature has proved very advantageous in complex samples like bone marrow aspirates or when a detailed analysis of a large number of events is required to identify a cluster of cells, as in rare event analysis, e.g. MRD samples.

The maturation tool opens new insights in evaluating the maturation patterns of different lineages based on different markers and is very relevant when there is a clinical suspicion of MDS. Finally the use of the compass tool enables new automated classification based on databases of normal samples or comprehensively pre-diagnosed cases of different clonal entities.

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